Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Bilimsel Danışma Kurulu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2013, Cilt 27, Sayı 1, Sayfa(lar) 001-011   
THE EFFECTS OF AGE FACTOR ON SARCOIDOSIS DISEASE
Belma AKBABA BAĞCI1, Sevinç BİLGİN2, Ümmühan SELVİ2, Murat YALÇINSOY2, Bilgen Begüm AFŞAR3, Sinem ATIK GÜNGÖR4, Esen AKKAYA2
1Kahramanmaraş Necip Fazıl Şehir Devlet Hastanesi, Göğüs Hastalıkları, Kahramanmaraş, Türkiye
2SB İstanbul Süreyyapaşa Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim-Arastırma Hastanesi, Göğüs hastalıkları, İstanbul, Türkiye
3Zonguldak Uzun Mehmet Göğüs ve Meslek Hastalıkları Hastanesi, Göğüs Hastalıkları, Zonguldak, Türkiye
4İstanbul Universal Çamlıca Hastanesi, Göğüs Hastalıkları, İstanbul, Türkiye
Keywords: Sarcoidosis, older patients, Clinical differences

Although sarcoidosis is known to be common between the ages of 20-30; with the advancement of diagnostic methods can be seen in over 50 years of age. Recent studies in patients older than 50 years old with sarcoidosis are remarkable.

Records of 164 sarcoidosis patients followed by us betweeen 1996-2005 were reviewed retrospectively. Patients were divided as 50 years old and over; 49 years old and under.

In 50 years old and over, there were 61 paitents (%37; mean age: 58,21 ± 7,3 years; F/M = 5/1) and in 49 years old and under 103 patients (%63 ; mean age: 38,3 ± 7,1 years; F/M= 6/4). In comparison between the groups; cough, sputum, hemoptysis, chest pain, constitutional symptoms were similar (p>0,05). Dispnea was significantly higher in 50 years old and over (p< 0,01). No differences were seen between pulmonary function tests, diffusion capacity, sarcoidosis stage and tuberculin skin test results in two groups (p>0,05). Angiotensin converting enzyme levels were lower in 50 years old and over (p=0,04). Extrapulmonary manifestations as peripheral lymphadenopathy, skin and eye involvement were similar (p>0,05). Ultrasonographically hepatomegaly and splenomegaly were significantly higher in 50 years old and over (p = 0.018).

As a result sarcoidosis is not special to young population. Despite the increase in studies on older patients with sarcoidosis, comparative studies with younger patients are not enough. We believe that as the clinical difference between different age groups are described, the diagnosis will be easier.