Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Bilimsel Danışma Kurulu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2016, Cilt 30, Sayı 2, Sayfa(lar) 075-080   
DIAGNOSTIC VALUE OF BLIND PLEURAL BIOPSY AND PET/CT IN MALIGNANT PLEURAL DISEASES
Kemal Can TERTEMİZ1, Aylin ÖZGEN ALPAYDIN1, Volkan KARAÇAM2, Atila AKKOCLU1
1Dokuz Eylül Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları AD, İzmir, Türkiye
2Dokuz Eylül Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi AD, İzmir, Türkiye
Keywords: Malignant pleural effusion, Blinded pleural biopsy, VATS, PET/CT

Aim: In this study we aimed to find out diagnostic value of blinded pleural biopsy and the role of PET/CT for distinction malingant or benign in patients with suspected malignant pleural effusion.

Material and Methods: Blinded pleural biopsy performed cases who are not able to diagnosed with cytologic examination with exudative pleural effusion are included to the study. Clinical properties, PET/CT and pathological results of the cases are analysed retrospectively. Diagnostic correlation of blinded pleural biopsy is evaluated in VATS biopsy performed cases.

Results: Ninty-eight cases are included to the study. As the results of blinded pleural biopsy; 62(63.2%) patients were diagnosed as benign, 24(25.9%) patients diagnosed as malignant, and 12(12.9%) patients as non-diagnostic sample. The sensitivity was 16%, spesifity was 100%, positive predicted value was 100%, negative predictive value was 52.2% and diagnostic accuracy was 56.2% for the blinded pleural biopsy. Malingancy was detected in 7 cases of PET/CT negative 16 cases. According to this findings the sensitivity was 78.7%, spesifity was 56.2%, positive predicted value was 78.7%, negative predictive value was 56.2% and diagnostic accuracy was 71.4% for PET/CT.

Conclusion: According to low diagnostic value of the blinded pleural biopsy in malignant pleural effusions thoracoscopic surgical biopsy should be performed as a first line diagnostic procedure in these cases. Blinded pleural biopsy should be used in cases with low clinical status cases and has in mind the low diagnostic sensitivity. PET/CT has low negative predictive value especialy in cases with extrathorasic malignancies for pleural invasion. So surgical biopsies should be performed also PET/CT negative cases.