Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Bilimsel Danışma Kurulu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2019, Cilt 33, Sayı 1, Sayfa(lar) 007-014   
EVALUATION OF CASES WITH VENTILATOR-ASSOCIATED PNEUMONIA CAUSED BY ACINETOBACTER BAUMANII AT A TERTIARY CARE HOSPITAL IN IZMIR
Sabri ATALAY1, Tuba KIŞ1, Ufuk SÖNMEZ2,Gürsel ERSAN1, Şükran KÖSE1
1Sağlık Bilimleri Üniversitesi Tepecik Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Izmir, Türkiye
2Sağlık Bilimleri Üniversitesi Bozyaka Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Izmir, Türkiye
Keywords: Acinetobacter baumannii, Intensive Care Units, Pneumonia, Ventilator-Associated

Aim: Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality. Recent data suggest that Acinetobacter baumannii (A. baumannii) is an important VAP pathogen in our country and in the world. This study aimed to evaluate the risk factors of VAP caused by A. baumannii in the intensive care unit (ICU), underlying diseases, susceptibility rates, treatment response and the factors affecting the treatment outcome.

Material and Methods: Patients who were diagnosed with VAP in the ICU and whom A. baumannii were grown in deep tracheal aspiration (DTA) cultures were evaluated, retrospectively.

Results: A total of forty-three cases diagnosed with VAP caused by A. baumannii were included in the study. Twenty-five (58%) of the cases were male, mean age was 66.8 (19-99) years. The rate of any chronic disease of the patients was 69.8% and the rate of antibiotic use in the previous month was 95.3%. The most susceptible antibiotics were as follows; 81.8% for colistin, 32.4% for levocloxacin and 11.6% for tigecycline, respectively. When the treatment outcome were evaluated; 18 (41.9%) patients were cured, five (11.6%) cases developed recurrence and 20 cases (46.5%) were died. There was no statistically significant difference between the clinical outcome and antibiotic history, PPI use, duration of MV application, leukocyte and CRP levels at the time of diagnosis and gender (p> 0.05).

Conclusion: As a conclusion; VAP caused by A. baumannii develops in patients with advanced age and who have chronic diseases, it has been found that the mortality is still high despite the combination antibiotic therapy.